ABCD Study® research publications cover a wide range of topics related to adolescent (teen) brain development, behavior, and health, including mental health and stress, physical activity, substance use, and psychosocial factors.

Our publications are authored by ABCD investigators, collaborators, and other researchers. The analysis methodologies, findings, and interpretations expressed in these publications are those of the authors and do not constitute an endorsement by the ABCD Study. The research publications listed here include empirical as well as non-empirical papers (e.g., focused review articles, editorials).

To align with widely accepted quality standards, this list includes only papers from journals that are indexed in one or more of the databases listed below. Learn about the selection process for each database:

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Title Journal Authors Year Details
Toggle Structural Genetic Variations Illuminate the Dimensional Landscape of Child Psychopathology and Cognition. The American journal of psychiatry Boen R, Bearden CE 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

The American journal of psychiatry

Published

2025/08/01

Authors

Boen R, Bearden CE

Keywords

Child/Adolescent Psychiatry,, Cognition, Development,, Genetics/Genomics,, Neurodevelopmental Disorders,

DOI

10.1176/appi.ajp.20250522
Toggle Genome-Wide Association Studies of Delay Discounting and Impulsive Personality Traits in Children From the Adolescent Behavior and Cognitive Development Study. Genes, brain, and behavior Deng WQ, Elsayed M, Belisario KL, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Genes, brain, and behavior

Published

2025/08/01

Authors

Deng WQ, Elsayed M, Belisario KL, Sanchez-Roige S, Palmer AA, MacKillop J

Keywords

DOI

10.1111/gbb.70033
Toggle School start times and racial disparities in early adolescent sleep. Sleep health Yip T, Yan J, Zhang MR, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Sleep health

Published

2025/07/31

Authors

Yip T, Yan J, Zhang MR, Wang Y, Zhao Z, Cham H, Alegría M

Keywords

ABCD Study, Disparities, School age population, Schools, Sleep duration

DOI

10.1016/j.sleh.2025.07.003
Toggle When Money Troubles Spill Over: Family Conflict and Children’s Problem Behaviors Journal of Child and Family Studies Aaron L & Black SR 2025
Link to publication

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Journal of Child and Family Studies

Published

2025/07/31

Authors

Aaron L & Black SR

Keywords

DOI

https://doi.org/10.1007/s10826-025-03111-1
Toggle Youth electronic media use and family conflict: Bidirectional associations across early adolescence. Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) Carvalho C, Ravindran N, Koss KJ 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43)

Published

2025/07/31

Authors

Carvalho C, Ravindran N, Koss KJ

Keywords

DOI

10.1037/fam0001390
Toggle Trajectories of psychotic-like experiences in youth and associations with lifestyle factors. Journal of child psychology and psychiatry, and allied disciplines Cooper R, van der Ven E, Jalbrzikowski M 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Journal of child psychology and psychiatry, and allied disciplines

Published

2025/07/29

Authors

Cooper R, van der Ven E, Jalbrzikowski M

Keywords

Psychotic‐like, adolescence, exercise, growth mixture modeling, lifestyle factors, sleep

DOI

10.1111/jcpp.14179
Toggle Genetic and neurobiological mechanisms underlying transition in self-injury thoughts and behaviours during adolescence. The British journal of psychiatry : the journal of mental science Wen X, Sun Y, Wang S, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

The British journal of psychiatry : the journal of mental science

Published

2025/07/28

Authors

Wen X, Sun Y, Wang S, Yue W, Chen R

Keywords

Self-injury, functional brain network, polygenic risk scores, structural brain, suicide

DOI

10.1192/bjp.2025.10300
Toggle Considerations in using heart rate-based physical activity estimates from consumer wearables in individuals with varying weight status. The international journal of behavioral nutrition and physical activity Brown DMY, Wing D, Pfledderer CD, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

The international journal of behavioral nutrition and physical activity

Published

2025/07/28

Authors

Brown DMY, Wing D, Pfledderer CD, Stoepker P, Fairclough SJ, Carlson JA

Keywords

Absolute intensity, Accelerometry, Adiposity, Fitness, Relative intensity, Wearable devices

DOI

10.1186/s12966-025-01801-z
Toggle Prenatal Substance Exposure and Obesity: Trajectories of Tri-Ponderal Mass Index in Early Adolescence. American journal of preventive medicine Li R, Wigley IM, Suuronen I, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

American journal of preventive medicine

Published

2025/07/26

Authors

Li R, Wigley IM, Suuronen I, Jolly A, Tuulari JJ

Keywords

DOI

10.1016/j.amepre.2025.107997
Toggle Measuring the Associations Between Brain Morphometry and Polygenic Risk Scores for Substance use Disorders in Drug-Naive Adolescents. Behavior genetics Kramer S, Su MH, Stephenson M, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Behavior genetics

Published

2025/07/25

Authors

Kramer S, Su MH, Stephenson M, Rabinowitz J, Maher B, Roberson-Nay R, Castro-de-Araujo LFS, Zhou Y, Neale MC, Gillespie NA

Keywords

Brain, Cerebral cortex, Polygenic risk, Substance use, Twin

DOI

10.1007/s10519-025-10227-z
Toggle Neighborhood conditions and neurodevelopment: A systematic review of brain structure in children and adolescents. Developmental cognitive neuroscience Lewis L, Gresham B, Riegelman A, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Developmental cognitive neuroscience

Published

2025/07/25

Authors

Lewis L, Gresham B, Riegelman A, Ip KI

Keywords

Brain structure, MRI, Neighborhoods, Systematic review, Youth

DOI

10.1016/j.dcn.2025.101600
Toggle DSI Studio: an integrated tractography platform and fiber data hub for accelerating brain research. Nature methods Yeh FC 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Nature methods

Published

2025/07/24

Authors

Yeh FC

Keywords

DOI

10.1038/s41592-025-02762-8
Toggle Dissecting human cortical similarity networks across the lifespan. Neuron Liang X, Sun L, Xia M, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Neuron

Published

2025/07/23

Authors

Liang X, Sun L, Xia M, Zhao T, Gong G, Li Q, Liao X, Cui Z, Duan D, Pang C, Wang Q, Yu Q, Bi Y, Chen P, Chen R, Chen Y, Chen T, Cheng J, Cheng Y, Dai Z, Deng Y, Ding Y, Dong Q, Gao JH, Gong Q, Han Y, Han Z, Huang CC, Huang R, Huo R, Li L, Lin CP, Lin Q, Liu B, Liu C, Liu N, Liu Y, Liu Y, Lu J, Ma L, Men W, Qin S, Qin W, Qiu J, Qiu S, Si T, Tan S, Tang Y, Tao S, Wang D, Wang F, Wang J, Wang J, Wang P, Wang X, Wang Y, Wei D, Wu Y, Xie P, Xu X, Xu Y, Xu Z, Yang L, Yu C, Yuan H, Zeng Z, Zhang H, Zhang X, Zhao G, Zheng Y, Zhong S, , , , He Y

Keywords

brain chart, connectome, cortical morphology, functional connectivity, individual difference, metabolism, morphometric network, morphometric similarity, normative model, transcriptome

DOI

10.1016/j.neuron.2025.06.018
Toggle Cognitive Control Decision-Making Dynamics Across Internalizing and Externalizing Symptoms in Youth. Research on child and adolescent psychopathology Warren SL, Malaiya RK, Drake OK, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Research on child and adolescent psychopathology

Published

2025/07/23

Authors

Warren SL, Malaiya RK, Drake OK, Tang A, Chandra NK

Keywords

Child behavior checklist, Childhood psychopathology, Drift–diffusion model, Executive function, Flanker, Inhibition

DOI

10.1007/s10802-025-01351-9
Toggle Latent Class Analysis of Household and Community Adversity Among Pre-Adolescent Youth in the United States. Child psychiatry and human development Choi KR, Dunn EC, Comulada WS, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Child psychiatry and human development

Published

2025/07/22

Authors

Choi KR, Dunn EC, Comulada WS, Saadi A

Keywords

Adversity, Community, Discrimination, Latent class analysis

DOI

10.1007/s10578-025-01883-7
Toggle Pubertal mediators of early life stress and age on adolescent alcohol initiation: Analysis by sex. Psychoneuroendocrinology Donovan A, Assari S, Grella C, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Psychoneuroendocrinology

Published

2025/07/20

Authors

Donovan A, Assari S, Grella C, Shaheen M, Richter L, Friedman TC

Keywords

Adolescence, Alcohol, Puberty, Sex, Stress, Substance use

DOI

10.1016/j.psyneuen.2025.107559
Toggle A pattern-learning algorithm associates copy number variations with brain structure and behavioural variables in an adolescent population cohort. Nature biomedical engineering Kopal J, Huguet G, Marotta J, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Nature biomedical engineering

Published

2025/07/18

Authors

Kopal J, Huguet G, Marotta J, Aggarwal S, Osayande N, Kumar K, Saci Z, Jean-Louis M, Chai XJ, Ge T, Yeo BTT, Thompson PM, Bearden CE, Andreassen OA, Jacquemont S, Bzdok D

Keywords

DOI

10.1038/s41551-025-01454-0
Toggle Neural correlates differ between crystallized and fluid intelligence in adolescents. Translational psychiatry Qiu B, Qian R, Gu B, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Translational psychiatry

Published

2025/07/17

Authors

Qiu B, Qian R, Gu B, Li Z, Chen Z, Xu X, Gao H, Chen Y, Zhao R, Chen R, Zhang Y, Zhang L, Zhao Z, Li M, Wu D

Keywords

DOI

10.1038/s41398-025-03467-4
Toggle Regions of Interest Assessment of Prenatal Exposure to Tobacco on Adolescent Cortical Thickness and Sulcal Depth. Behavioural brain research Kochvar A, Laviolette SR, Khan AS, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Behavioural brain research

Published

2025/07/16

Authors

Kochvar A, Laviolette SR, Khan AS, Grin B, Dai HD

Keywords

Brain morphology, Childhood and adolescence, Maternal tobacco use

DOI

10.1016/j.bbr.2025.115741
Toggle Longer scans boost prediction and cut costs in brain-wide association studies. Nature Ooi LQR, Orban C, Zhang S, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Nature

Published

2025/07/16

Authors

Ooi LQR, Orban C, Zhang S, Nichols TE, Tan TWK, Kong R, Marek S, Dosenbach NUF, Laumann TO, Gordon EM, Yap KH, Ji F, Chong JSX, Chen C, An L, Franzmeier N, Roemer-Cassiano SN, Hu Q, Ren J, Liu H, Chopra S, Cocuzza CV, Baker JT, Zhou JH, Bzdok D, Eickhoff SB, Holmes AJ, Yeo BTT

Keywords

DOI

10.1038/s41586-025-09250-1
Toggle Predicting the First Onset of Suicidal Thoughts and Behaviors in Adolescents Using Multimodal Risk Factors: A Four-Year Longitudinal Study. Journal of the American Academy of Child and Adolescent Psychiatry Nguyen J, Dwyer D, Toenders YJ, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Journal of the American Academy of Child and Adolescent Psychiatry

Published

2025/07/15

Authors

Nguyen J, Dwyer D, Toenders YJ, Tagliaferri SD, van Velzen LS, Clark SR, Scott I, Hartmann S, Wigman JTW, Lin A, Thompson AD, Wannan CMJ, Gao CX, Wood SJ, Amminger GP, Yung AR, Koutsouleris N, Hartmann JA, Yuen HP, Davey CG, Ronald A, McGorry PD, Middeldorp C, Nelson B, Schmaal L

Keywords

adolescents, longitudinal, machine learning, prediction, suicide

DOI

10.1016/j.jaac.2025.07.006
Toggle Integrating multilevel, multidomain and multimodal neuroimaging factors to predict early alcohol exposure trajectories using explainable AI. Developmental cognitive neuroscience Ferariu A, Chang H, Kumar A, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Developmental cognitive neuroscience

Published

2025/07/15

Authors

Ferariu A, Chang H, Kumar A, Sahl A, Gorka S, Wang L, Thompson WK, Zhang F

Keywords

Early alcohol exposure, Longitudinal latent patterns, Machine learning, Multilevel risk factors, Multimodal neuroimaging

DOI

10.1016/j.dcn.2025.101597
Toggle Examining Deviant Peer Association as a Predictor of Dual Systems Model Development: Testing for Moderation Effects of Age American Journal of Criminal Justice Wojciechowski, T 2025
Link to publication

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

American Journal of Criminal Justice

Published

2025/07/11

Authors

Wojciechowski, T

Keywords

Dual systems model; Deviant peer association; Age; Development

DOI

https://doi.org/10.1007/s12103-025-09842-7
Toggle Associations between sleep, obesity, and mental health in adolescents: Understanding sex-specific vulnerabilities. Journal of affective disorders Kiss O, Harkness A, Müller-Oehring EM, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Journal of affective disorders

Published

2025/07/11

Authors

Kiss O, Harkness A, Müller-Oehring EM, Nagata JM, Baker FC

Keywords

Adolescents, Mental health, Obesity, Sleep, Sleep problems

DOI

10.1016/j.jad.2025.119883
Toggle Genetic liability to major psychiatric disorders contributes to multi-faceted quality of life outcomes in children and adults. Translational psychiatry Shi Y, Mota NR, Franke B, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Translational psychiatry

Published

2025/07/07

Authors

Shi Y, Mota NR, Franke B, Sprooten E

Keywords

DOI

10.1038/s41398-025-03443-y
Toggle Genetic, psychological, and environmental factors are uniquely associated with onset of alcohol use in the adolescent brain cognitive development (ABCD) study. Translational psychiatry Choi M, Aliev F, Barr PB, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Translational psychiatry

Published

2025/07/05

Authors

Choi M, Aliev F, Barr PB, Cooke ME, Kuo SI, Salvatore JE, Dick DM, Brislin SJ

Keywords

DOI

10.1038/s41398-025-03454-9
Toggle Genetic risk-dependent brain markers of resilience to childhood Trauma. Nature communications Lu H, Rolls ET, Liu H, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Nature communications

Published

2025/07/05

Authors

Lu H, Rolls ET, Liu H, Stein DJ, Sahakian BJ, Elliott R, Jia T, Xie C, Xiang S, Wang N, Banaschewski T, Bokde ALW, Desrivières S, Flor H, Grigis A, Garavan H, Heinz A, Brühl R, Martinot JL, Martinot MP, Artiges E, Nees F, Orfanos DP, Lemaitre H, Poustka L, Hohmann S, Holz N, Fröhner JH, Smolka MN, Vaidya N, Walter H, Whelan R, Schumann G, Feng J, Luo Q

Keywords

DOI

10.1038/s41467-025-61471-0
Toggle Large-scale examination of hot and cool executive function in children born preterm. Developmental cognitive neuroscience Menu I, Duffy M, Bhatia T, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Developmental cognitive neuroscience

Published

2025/07/05

Authors

Menu I, Duffy M, Bhatia T, Trapaga S, John J, Music S, Nicholas D, Yim S, Thomason ME

Keywords

ABCD study, Brain-behavior, Executive functions, Hot and cool executive functions, Preterm birth

DOI

10.1016/j.dcn.2025.101593
Toggle Brain Functional Connectivity Mediates the Association Between Adverse Childhood Experiences and Conduct Problems. Biological psychiatry. Cognitive neuroscience and neuroimaging Liu P, Song D, Guo Y, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Biological psychiatry. Cognitive neuroscience and neuroimaging

Published

2025/07/05

Authors

Liu P, Song D, Guo Y, Zhang H

Keywords

Adolescent Brain Cognitive Development (ABCD), Adverse Childhood Experiences, Brian Network Connectivity, Conduct Problems, Connectome-Based Predictive Modeling, Mediation Analysis

DOI

10.1016/j.bpsc.2025.06.007
Toggle Prospective Predictors of Adolescent Screen Time and Problematic Screen Use JAACAP Open Grunt BA & Luciana M 2025
Link to publication

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

JAACAP Open

Published

2025/07/03

Authors

Grunt BA & Luciana M

Keywords

addiction; digital media; impulsivity; motivation; psychopathology

DOI

https://doi.org/10.1016/j.jaacop.2025.06.007
Toggle Social profiles among youth with attention-deficit/hyperactivity disorder (ADHD): Evidence from the ABCD study. Developmental cognitive neuroscience Pintos Lobo R, Peraza JA, Salo T, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Developmental cognitive neuroscience

Published

2025/07/03

Authors

Pintos Lobo R, Peraza JA, Salo T, Meca A, Smith DD, Feeney KE, Schmarder KM, Sutherland MT, Gonzalez R, Musser ED, Laird AR

Keywords

Attention-deficit/hyperactivity disorder, Brain networks, Research domain criteria, Resting state functional, connectivity, Social functioning

DOI

10.1016/j.dcn.2025.101591
Toggle Examining recent effects of caffeine on default mode network and dorsal attention network anticorrelation in youth. PloS one Ware OD, Chang SE, Thompson WK, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

PloS one

Published

2025/07/02

Authors

Ware OD, Chang SE, Thompson WK, Potter AS, Garavan H, Johnson ME, Uddin LQ

Keywords

DOI

10.1371/journal.pone.0327385
Toggle The association of witnessing violence with alcohol and cannabis expectancies among Black, Latinx, and White youth: considering neighborhood context. Social psychiatry and psychiatric epidemiology Sartor CE, Kennelly N, Powell MZ, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Social psychiatry and psychiatric epidemiology

Published

2025/07/02

Authors

Sartor CE, Kennelly N, Powell MZ, Chung T, Latendresse SJ, McCutcheon VV

Keywords

Black, Latinx, Substance use expectancies, Witnessing violence, Youth

DOI

10.1007/s00127-025-02939-8
Toggle Addressing artifactual bias in large, automated MRI analyses of brain development. Nature neuroscience Elyounssi S, Kunitoki K, Clauss JA, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Nature neuroscience

Published

2025/07/01

Authors

Elyounssi S, Kunitoki K, Clauss JA, Laurent E, Kane KA, Hughes DE, Hopkinson CE, Bazer O, Sussman RF, Doyle AE, Lee H, Tervo-Clemmens B, Eryilmaz H, Hirschtick RL, Barch DM, Satterthwaite TD, Dowling KF, Roffman JL

Keywords

DOI

10.1038/s41593-025-01990-7
Toggle Analysis of Longitudinal Change Patterns in Developing Brain Using Functional and Structural Magnetic Resonance Imaging via Multimodal Fusion. Human brain mapping Saha R, Saha DK, Fu Z, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Human brain mapping

Published

2025/07/01

Authors

Saha R, Saha DK, Fu Z, Duda M, Silva RF, Wilson TW, Wang YP, Stephen JM, Calhoun VD

Keywords

DOI

10.1002/hbm.70241
Toggle Sex-specific trajectories of adolescent brain development and behavioral health in relation to family environments. Psychiatry research Liu Y, Wang M, Li F, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Psychiatry research

Published

2025/07/01

Authors

Liu Y, Wang M, Li F, Zhang L, Zhang Q, Zhou W, Du W, Luo Q, Ren T, Li F

Keywords

Adolescent, Brain, Externalizing symptoms, Family environment, Internalizing symptoms, Sex Differences

DOI

10.1016/j.psychres.2025.116609
Toggle Neuroinflammation and Obesity in the ABCD Study. JAMA network open Hall PA 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

JAMA network open

Published

2025/07/01

Authors

Hall PA

Keywords

DOI

10.1001/jamanetworkopen.2025.22751
Toggle Prefrontal activity to negative emotions moderates the longitudinal links between parents and youth's internalizing symptoms. Cerebral cortex (New York, N.Y. : 1991) Shi Z, Yang B, Zhou Z, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Cerebral cortex (New York, N.Y. : 1991)

Published

2025/07/01

Authors

Shi Z, Yang B, Zhou Z, Haase CM, Qu Y

Keywords

anxiety symptoms, depressive symptoms, emotion regulation, prefrontal cortex

DOI

10.1093/cercor/bhaf170
Toggle Distinct Patterns of Weight Gain, Age, and Subcortical Microstructure in Early Adolescence. JAMA network open Adise S, Li ZA, Ottino-González J, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

JAMA network open

Published

2025/07/01

Authors

Adise S, Li ZA, Ottino-González J, Morys F, Chiarelli PA, Hershey T

Keywords

DOI

10.1001/jamanetworkopen.2025.22211
Toggle Psychopathology and Gaming Disorder in Adolescents. JAMA network open Falcione K, Weber R 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

JAMA network open

Published

2025/07/01

Authors

Falcione K, Weber R

Keywords

DOI

10.1001/jamanetworkopen.2025.28532
Toggle High-dimensional Subgroup Regression Analysis. Statistica Sinica Jiang F, Tian L, Kang J, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Statistica Sinica

Published

2025/07/01

Authors

Jiang F, Tian L, Kang J, Li L

Keywords

Adolescent Brain Cognitive Development Study, Functional magnetic resonance imaging, Group Lasso, High-dimensional regressions, Subgroup analysis

DOI

10.5705/ss.202023.0075
Toggle Parental psychopathology, family conflict, brain function, and child autistic-like traits in early adolescents. Psychological medicine Wang M, Liu Y, Zhu T, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Psychological medicine

Published

2025/06/30

Authors

Wang M, Liu Y, Zhu T, Huang R, Huang L, Zhang L, Zhang Q, Sun Y, Zhou W, Pu Y, Chen J, He H, Wang S, Chen W, Zhang Q, Luo Q, Ren T, Li F

Keywords

adolescents, autistic-like traits, family conflict, functional brain connectivity, parental psychopathology, polygenic risk score

DOI

10.1017/S0033291725100779
Toggle Associations of neighborhood threat and deprivation with psychopathology: Uncovering neural mechanisms. Development and psychopathology Vargas TG, Rakesh D, McLaughlin KA 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Development and psychopathology

Published

2025/06/30

Authors

Vargas TG, Rakesh D, McLaughlin KA

Keywords

brain, deprivation, development, neighborhood, threat

DOI

10.1017/S095457942510031X
Toggle Supervised brain node and network construction under voxel-level functional imaging. Imaging neuroscience (Cambridge, Mass.) Xu W, Wang S, Gao S, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Imaging neuroscience (Cambridge, Mass.)

Published

2025/06/26

Authors

Xu W, Wang S, Gao S, Tian X, Tan C, Shen X, Luo W, Constable T, Li T, Zhao Y

Keywords

brain atlas, connectome-based predictive model, fMRI, functional connectivity, spectral clustering, supervised learning

DOI

10.1162/IMAG.a.56
Toggle Polygenic Risk, Psychopathology, and Personalized Functional Brain Network Topography in Adolescence. JAMA psychiatry Sun KY, Schmitt JE, Moore TM, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

JAMA psychiatry

Published

2025/06/25

Authors

Sun KY, Schmitt JE, Moore TM, Barzilay R, Almasy L, Schultz LM, Mackey AP, Kafadar E, Sha Z, Seidlitz J, Mallard TT, Cui Z, Li H, Fan Y, Fair DA, Satterthwaite TD, Keller AS, Alexander-Bloch A

Keywords

DOI

10.1001/jamapsychiatry.2025.1258
Toggle Ethnic Discrimination's Role on Increased Substance Susceptibility and Use Among US Youth. American journal of preventive medicine Rosales R, Veliz P, Jardine J, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

American journal of preventive medicine

Published

2025/06/25

Authors

Rosales R, Veliz P, Jardine J, Weigard AS, McCabe SE

Keywords

Alcohol use, Cannabis use, Discrimination, Tobacco use, Youth

DOI

10.1016/j.amepre.2025.107956
Toggle Prior externalizing, but not internalizing, symptoms predict subsequent family conflict in emerging adolescence: A longitudinal study. Development and psychopathology Aaron L, Black SR 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Development and psychopathology

Published

2025/06/25

Authors

Aaron L, Black SR

Keywords

Family conflict, externalizing symptoms, internalizing symptoms, latent growth curve modeling with structured residuals

DOI

10.1017/S0954579425100278
Toggle A Bayesian Regularized and Annotation-Informed Integrative Analysis of Cognition (BRAINIAC). Developmental cognitive neuroscience Zablocki RW, Xu B, Fan CC, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Developmental cognitive neuroscience

Published

2025/06/25

Authors

Zablocki RW, Xu B, Fan CC, Thompson WK

Keywords

ABCD Study, Annotations, Bayesian modeling, Variance components, Whole-brain analyses

DOI

10.1016/j.dcn.2025.101569
Toggle Identifying Risk and Protective Factors Impacting the Clinical Outcomes of Subthreshold Anxiety in Early Adolescents: Insights From the ABCD Study. Depression and anxiety Keyin C, Qian L, Jiayuan Z, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Depression and anxiety

Published

2025/06/25

Authors

Keyin C, Qian L, Jiayuan Z, Lijing N, Haowei D, Lanxin P, Xingqin W, Qing M, Ruibin Z

Keywords

adolescent brain and cognitive development study, anxiety disorder, prevention, prognosis, remission, subthreshold anxiety

DOI

10.1155/da/6514030
Toggle Cognition is associated with task-related brain network reconfiguration in late childhood. Developmental cognitive neuroscience Mitchell ME, Jaimes AJ, Nugiel T 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Developmental cognitive neuroscience

Published

2025/06/24

Authors

Mitchell ME, Jaimes AJ, Nugiel T

Keywords

Brain networks, Functional connectivity, Reconfiguration, Response inhibition, Resting state, Working memory

DOI

10.1016/j.dcn.2025.101589
Toggle Screen Use in Late Childhood and Early Adolescence-A Search for Balance. JAMA pediatrics Alfano CA, Moreno JP 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

JAMA pediatrics

Published

2025/06/23

Authors

Alfano CA, Moreno JP

Keywords

DOI

10.1001/jamapediatrics.2025.1726
Toggle The association of objectively and subjectively measured modifiable lifestyle factors with internalizing problems: the role of genetic confounding and shared method variance bias. Social psychiatry and psychiatric epidemiology Zhang Y, Choi KW, Frach L, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Social psychiatry and psychiatric epidemiology

Published

2025/06/23

Authors

Zhang Y, Choi KW, Frach L, Robinson E, Ge T, Pingault JB, Tiemeier H

Keywords

Adolescent internalizing problems, Genetic confounding, Modifiable lifestyle, Shared method variance

DOI

10.1007/s00127-025-02952-x
Toggle Role of Sleep and White Matter in the Link Between Screen Time and Depression in Childhood and Early Adolescence. JAMA pediatrics Lima Santos JP, Soehner AM, Biernesser CL, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

JAMA pediatrics

Published

2025/06/23

Authors

Lima Santos JP, Soehner AM, Biernesser CL, Ladouceur CD, Versace A

Keywords

DOI

10.1001/jamapediatrics.2025.1718
Toggle Associations among socioeconomic disadvantage, longitudinal changes in within-network connectivity, and academic outcomes in the ABCD study. Developmental cognitive neuroscience Rakesh D, Sadikova E, McLaughlin KA 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Developmental cognitive neuroscience

Published

2025/06/23

Authors

Rakesh D, Sadikova E, McLaughlin KA

Keywords

ABCD study, Academic achievement, Childhood and adolescence, Resting state functional connectivity, Socioeconomic status

DOI

10.1016/j.dcn.2025.101587
Toggle We need to know more, much more about sports participation in adolescents. Pediatric research Agostinete RR, Almeida-Correa V, Ribeiro-de-Oliveira AV, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Pediatric research

Published

2025/06/20

Authors

Agostinete RR, Almeida-Correa V, Ribeiro-de-Oliveira AV, Bertacine-Neto P, Rios-Cordeiro L, Galbiatti-Nunes T, Gonçalves-Neto A, Fernandes RA

Keywords

DOI

10.1038/s41390-025-04240-5
Toggle Reproducible sex differences in personalised functional network topography in youth. The British journal of psychiatry : the journal of mental science Keller AS, Sun KY, Francisco A, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

The British journal of psychiatry : the journal of mental science

Published

2025/06/19

Authors

Keller AS, Sun KY, Francisco A, Robinson H, Beydler E, Bassett DS, Cieslak M, Cui Z, Davatzikos C, Fan Y, Gardner M, Kishton R, Kornfield SL, Larsen B, Li H, Linder I, Pines A, Pritschet L, Raznahan A, Roalf DR, Seidlitz J, Shafiei G, Shinohara RT, White LK, Wolf DH, Alexander-Bloch A, Satterthwaite TD, Shanmugan S

Keywords

Sex differences, brain networks, development, precision brain mapping, youth

DOI

10.1192/bjp.2025.135
Toggle Beyond Screen Time-Addictive Screen Use Patterns and Adolescent Mental Health. JAMA Nagata JM, Helmer CK, Al-Shoaibi AA 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

JAMA

Published

2025/06/18

Authors

Nagata JM, Helmer CK, Al-Shoaibi AA

Keywords

DOI

10.1001/jama.2025.8135
Toggle Addictive Screen Use Trajectories and Suicidal Behaviors, Suicidal Ideation, and Mental Health in US Youths. JAMA Xiao Y, Meng Y, Brown TT, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

JAMA

Published

2025/06/18

Authors

Xiao Y, Meng Y, Brown TT, Keyes KM, Mann JJ

Keywords

DOI

10.1001/jama.2025.7829
Toggle Linking pregnancy- and birth-related risk factors to a multivariate fusion of child cortical structure. Proceedings of the National Academy of Sciences of the United States of America Lindseth LRS, Beck D, Westlye LT, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Proceedings of the National Academy of Sciences of the United States of America

Published

2025/06/17

Authors

Lindseth LRS, Beck D, Westlye LT, Tamnes CK, Norbom LB

Keywords

MRI, cortical morphology, neurodevelopment, perinatal, prenatal

DOI

10.1073/pnas.2422281122
Toggle The longitudinal impact of screen media activities on brain function, architecture and mental health in early adolescence. International journal of clinical and health psychology : IJCHP Dong N, Zhou Y, Lei L, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

International journal of clinical and health psychology : IJCHP

Published

2025/06/14

Authors

Dong N, Zhou Y, Lei L, Lee TMC, Lam CLM

Keywords

Adolescence, Brain functional connectivity, Longitudinal, Screen media activity

DOI

10.1016/j.ijchp.2025.100589
Toggle Copy Number Variant Architecture of Child Psychopathology and Cognitive Development in the ABCD Study. The American journal of psychiatry Sha Z, Sun KY, Jung B, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

The American journal of psychiatry

Published

2025/06/11

Authors

Sha Z, Sun KY, Jung B, Barzilay R, Moore TM, Almasy L, Forsyth JK, Prem S, Gandal MJ, Seidlitz J, Glessner JT, Alexander-Bloch AF

Keywords

Child/Adolescent Psychiatry, Genetics/Genomics, Neurodevelopmental Disorders

DOI

10.1176/appi.ajp.20240445
Toggle Abnormal association between neural activity and genetic expressions of impulsivity in attention deficit hyperactivity disorder: an Adolescent Brain Cognitive Development study. Biological psychiatry. Cognitive neuroscience and neuroimaging Jeon S, Kang JE, Hwang J, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Biological psychiatry. Cognitive neuroscience and neuroimaging

Published

2025/06/11

Authors

Jeon S, Kang JE, Hwang J, Calhoun VD, Lee JH

Keywords

Attention deficit hyperactivity disorder, functional magnetic resonance imaging, gene expression, imaging genetics, parallel independent component analysis, stop signal task

DOI

10.1016/j.bpsc.2025.06.002
Toggle Social epidemiology of bedtime screen use behaviors and sleep outcomes in early adolescence. Sleep health Nagata JM, Shim J, Ramappa S, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Sleep health

Published

2025/06/09

Authors

Nagata JM, Shim J, Ramappa S, Deshpande I, Low P, Kiss O, Ganson KT, Testa A, He J, Baker FC

Keywords

Adolescent, Digital technology, Mobile phone, Screen time, Sexual orientation, Sleep

DOI

10.1016/j.sleh.2025.05.005
Toggle Independent and Joint Prospective Associations of Screen Time and Sleep Disturbance with Body Mass Index and Waist Circumference Among U.S. Adolescents. Childhood obesity (Print) Al-Shoaibi AA, Helmer CK, Shim J, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Childhood obesity (Print)

Published

2025/06/06

Authors

Al-Shoaibi AA, Helmer CK, Shim J, Choi W, Dooley EE, Gooding HC, Pettee Gabriel K, Baker FC, Nagata JM

Keywords

body mass index, digital media, obesity, screens, waist circumference

DOI

10.1089/chi.2025.0022
Toggle Perception of social experiences and cortical thickness change together throughout early adolescence: Findings from the ABCD cohort. Imaging neuroscience (Cambridge, Mass.) Bates KE, Pollmann A, Kievit RA, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Imaging neuroscience (Cambridge, Mass.)

Published

2025/06/06

Authors

Bates KE, Pollmann A, Kievit RA, Fuhrmann D

Keywords

ABCD, adolescence, cortical development, puberty, social experiences, structural equation modelling

DOI

10.1162/IMAG.a.27
Toggle Brain wiring economics, network organisation and population-level genomics. Imaging neuroscience (Cambridge, Mass.) Monaghan A, Akarca D, Astle DE 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Imaging neuroscience (Cambridge, Mass.)

Published

2025/06/04

Authors

Monaghan A, Akarca D, Astle DE

Keywords

general intelligence, generative modelling, graph theory, polygenic scores, structural connectivity, the ABCD study

DOI

10.1162/IMAG.a.31
Toggle Upper Airway Volume Predicts Brain Structure and Cognition in Adolescents. American journal of respiratory and critical care medicine Kanhere A, Navarathna N, Yi PH, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

American journal of respiratory and critical care medicine

Published

2025/06/03

Authors

Kanhere A, Navarathna N, Yi PH, Parekh VS, Pickle J, Cloak CC, Ernst T, Chang L, Li D, Redline S, Isaiah A

Keywords

airway volume, brain volume, cognition, deep learning, sleep disordered breathing

DOI

10.1164/rccm.202409-1748OC
Toggle Outdoor Air Pollution Is Related to Amygdala Subregion Volume and Apportionment in Early Adolescence. Biological psychiatry global open science Morrel J, Overholtzer LN, Sukumaran K, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Biological psychiatry global open science

Published

2025/06/03

Authors

Morrel J, Overholtzer LN, Sukumaran K, Cotter DL, Cardenas-Iniguez C, Tyszka JM, Schwartz J, Hackman DA, Chen JC, Herting MM

Keywords

ABCD Study, Air pollution, Amygdala, Brain development, Neuroimaging, PM2.5

DOI

10.1016/j.bpsgos.2025.100544
Toggle Assessing the association between ADHD and brain maturation in late childhood and emotion regulation in early adolescence. Translational psychiatry Ágrez K, Vakli P, Weiss B, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Translational psychiatry

Published

2025/06/02

Authors

Ágrez K, Vakli P, Weiss B, Vidnyánszky Z, Bunford N

Keywords

DOI

10.1038/s41398-025-03411-6
Toggle The relationship between sleep and problem behaviors in children with attention-deficit/hyperactivity disorder. European journal of pediatrics Ghanim F, Harkness K, Wiley B, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

European journal of pediatrics

Published

2025/06/02

Authors

Ghanim F, Harkness K, Wiley B, Guadagni V, Murias K

Keywords

ADHD, Inattention, Problem behavior, Sleep

DOI

10.1007/s00431-025-06209-2
Toggle Smaller Subcortical Volume in Reward Processing Regions Precedes Weight Gain in Youth With High Financial Adversity: Findings From the Adolescent Brain Cognitive Development Study. The Journal of adolescent health : official publication of the Society for Adolescent Medicine Adise S, Machle CJ, Myers KP, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

The Journal of adolescent health : official publication of the Society for Adolescent Medicine

Published

2025/06/02

Authors

Adise S, Machle CJ, Myers KP, Ottino-González J, Millstein J, Goran MI, Sowell ER

Keywords

DOI

10.1016/j.jadohealth.2025.03.019
Toggle Altered neurobehavioral reward response predicts psychotic-like experiences in youth exposed to cannabis prenatally. Biological psychiatry Amir CM, Ghahremani DG, Chang SE, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Biological psychiatry

Published

2025/06/02

Authors

Amir CM, Ghahremani DG, Chang SE, Cooper ZD, Bearden CE

Keywords

cannabis, cannabis use disorder, neurodevelopment, psychosis, reward responsivity, schizophrenia

DOI

10.1016/j.biopsych.2025.05.019
Toggle On the Use of Auxiliary Variables in Multilevel Regression and Poststratification. Statistical science : a review journal of the Institute of Mathematical Statistics Si Y 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Statistical science : a review journal of the Institute of Mathematical Statistics

Published

2025/06/02

Authors

Si Y

Keywords

data integration, model-based, nonprobability sample, robust inference, selection/nonresponse bias

DOI

10.1214/24-sts932
Toggle Association of social and environmental exposures at the neighborhood level with child brain volume. Environment international Dimitrov LV, Christensen GM, Ku BS, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Environment international

Published

2025/06/02

Authors

Dimitrov LV, Christensen GM, Ku BS, Risk BB, Huels A

Keywords

Air pollution, Area deprivation, Brain, Children, Neighborhood exposome

DOI

10.1016/j.envint.2025.109576
Toggle Prenatal Tobacco and Alcohol Exposure and Cortical Change Among Youths. JAMA network open Marshall AT, Adise S, Kan EC, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

JAMA network open

Published

2025/06/02

Authors

Marshall AT, Adise S, Kan EC, Sowell ER

Keywords

DOI

10.1001/jamanetworkopen.2025.16729
Toggle Exploring Behavioural Patterns in Youth Predisposed to Bipolar Disorder and the Role of Interpersonal Trauma Using the Adolescent Brain Cognitive Development (ABCD) Dataset. Early intervention in psychiatry Ghaleb C, Penney D, Lavigne KM, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Early intervention in psychiatry

Published

2025/06/01

Authors

Ghaleb C, Penney D, Lavigne KM, Raucher-Chéné D

Keywords

adverse childhood experience, anxiety, bipolar disorder, children, depression, mania, mental disorders, risk factor

DOI

10.1111/eip.70058
Toggle Timing matters: A multi-contextual, within-individual approach to understanding age-related changes in psychopathology in the ABCD Study. Journal of research on adolescence : the official journal of the Society for Research on Adolescence Brieant A, Simmons C 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Journal of research on adolescence : the official journal of the Society for Research on Adolescence

Published

2025/06/01

Authors

Brieant A, Simmons C

Keywords

age‐varying, externalizing, family, internalizing, neighborhood, school, sex

DOI

10.1111/jora.70030
Toggle Social Connectedness and Neurodevelopmental Functioning in Youth: Insights from the ABCD Study. Advances in neurodevelopmental disorders Cosgrove KT, Rhudy JL, Morris AS, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Advances in neurodevelopmental disorders

Published

2025/05/31

Authors

Cosgrove KT, Rhudy JL, Morris AS, Thompson WK, Mosconi M, Paulus MP, Aupperle RL

Keywords

ABCD Study®, Executive function, Extracurricular involvement, Neurodevelopmental disorders, Parenting

DOI

10.1007/s41252-025-00448-y
Toggle Initial Subjective Response to Nicotine Vaping Predicts Subsequent E-Cigarette Use in Early Adolescence: An ABCD Investigation. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco Courtney KE, Nguyen-Louie TT, Thompson W, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

Published

2025/05/29

Authors

Courtney KE, Nguyen-Louie TT, Thompson W, Wade NE, Robledo Gonzalez M, Jacobus J, Doran N

Keywords

DOI

10.1093/ntr/ntaf116
Toggle Fine particulate matter air pollution and longitudinal gray matter development changes during early adolescence: variation by neighborhood disadvantage level. Environment international de Jesus AV, Ahmadi H, Hackman DA, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Environment international

Published

2025/05/29

Authors

de Jesus AV, Ahmadi H, Hackman DA, Cardenas-Iniguez C, Schachner J, Schwartz J, Gauderman WJ, Chen JC, Herting MM

Keywords

Adolescence, Brain development, Longitudinal, Magnetic resonance imaging, Neighborhood socioeconomic status, Particulate matter

DOI

10.1016/j.envint.2025.109561
Toggle Socioeconomic factors, brain-derived neurotrophic factor Val66Met polymorphism, and cortical structure in children and adolescents. Scientific reports Merz EC, Morys F, Hansen M, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Scientific reports

Published

2025/05/29

Authors

Merz EC, Morys F, Hansen M, Strack J, Jacobs L, Vainik U, Shishikura M, Myers B

Keywords

Cortical surface area, Cortical thickness, Family income, Gene-by-environment interaction, Neurotrophins, Parental education

DOI

10.1038/s41598-025-04081-6
Toggle Prevalence of Suicidal Ideation and Suicide Attempts by Race and Gender in Three Large U.S. Adolescent Cohorts. The American journal of psychiatry Cooper AM, Visoki E, Tran KT, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

The American journal of psychiatry

Published

2025/05/28

Authors

Cooper AM, Visoki E, Tran KT, Elbaz E, Gataviņš MM, McKetta S, Fein JA, Benton TD, Barzilay R

Keywords

Child/Adolescent Psychiatry, Disparities, Suicide and Self-Harm

DOI

10.1176/appi.ajp.20240735
Toggle Parental substance use history density and its influence on reward anticipation brain activation in late childhood and early adolescence. Developmental cognitive neuroscience Navarro-Love GY, Stinson EA, Sullivan RM, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Developmental cognitive neuroscience

Published

2025/05/28

Authors

Navarro-Love GY, Stinson EA, Sullivan RM, Lisdahl KM

Keywords

ABCD study, FMRI, Monetary incentive delay task, Parental Substance Use, Reward anticipation, Striatum

DOI

10.1016/j.dcn.2025.101572
Toggle Brain-wide associations of reaction time variability in the ABCD study. Imaging neuroscience (Cambridge, Mass.) Maloney TC, Dudley JA, Karalunas SL, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Imaging neuroscience (Cambridge, Mass.)

Published

2025/05/28

Authors

Maloney TC, Dudley JA, Karalunas SL, Atluri G, Simon JO, Tamm L, Epstein JN

Keywords

attentional fluctuations, intra-individual variability, intra-subject variation in reaction time, variance time course, vigilance

DOI

10.1162/IMAG.a.18
Toggle Unlocking the potential of wearable technology: Fitbit-derived measures for predicting ADHD in adolescents. Frontiers in child and adolescent psychiatry Rahman MM 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Frontiers in child and adolescent psychiatry

Published

2025/05/22

Authors

Rahman MM

Keywords

ADHD, adolescent mental health, fitbit-derived physical activity, machine learning, wearable technology

DOI

10.3389/frcha.2025.1504323
Toggle Associations between structural stigma and earlier pubertal timing persist for 1 year among Black girls and Latinx youth. Scientific reports Martino RM, Hollinsaid NL, Colich NL, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Scientific reports

Published

2025/05/21

Authors

Martino RM, Hollinsaid NL, Colich NL, McLaughlin KA, Hatzenbuehler ML

Keywords

Childhood and adolescence, Development, Puberty, Social determinants of health, Structural stigma

DOI

10.1038/s41598-025-00378-8
Toggle Differentiation of Executive Functions During Adolescence: Converging Evidence from Behavioral, Genetic and Neural Data. Biological psychology Yin R, Wang X, Zhao X, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Biological psychology

Published

2025/05/21

Authors

Yin R, Wang X, Zhao X, Chen C, Dong Q, Wang Q, Fang Y, Chen C

Keywords

CPM, Executive functions, GWAS, MRI, TWAS

DOI

10.1016/j.biopsycho.2025.109058
Toggle Cyberbullying, mental health, and substance use experimentation among early adolescents: a prospective cohort study. Lancet regional health. Americas Nagata JM, Shim J, Balasubramanian P, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Lancet regional health. Americas

Published

2025/05/20

Authors

Nagata JM, Shim J, Balasubramanian P, Leong AW, Smith-Russack Z, Shao IY, Al-Shoaibi AAA, Helmer CK, Ganson KT, Testa A, Kiss O, He J, Groves AK, Baird S, Baker FC

Keywords

Adolescents, Cyberbullying, Mental health, Social media, Substance use, Suicide, Victimization

DOI

10.1016/j.lana.2025.101002
Toggle Cross-sectional mega-analysis of resting-state alterations associated with autism and attention-deficit/hyperactivity disorder in children and adolescents Nature Mental Health Normal LJ, Sudre G, Bouyssi-Kobar M, et al. 2025
Link to publication

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Nature Mental Health

Published

2025/05/19

Authors

Normal LJ, Sudre G, Bouyssi-Kobar M, Jiao M, Gligorovic S, Jean J, White T, & Shaw P

Keywords

DOI

https://doi.org/10.1038/s44220-025-00431-5
Toggle Sustained breastfeeding associations with brain structure and cognition from late childhood to early adolescence. Pediatric research González JO, Fernández MAR, Esaian S, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Pediatric research

Published

2025/05/17

Authors

González JO, Fernández MAR, Esaian S, Rajagopalan V, Bouhrara M, Goran MI, Adise S

Keywords

DOI

10.1038/s41390-025-04086-x
Toggle Longitudinal and Geographic Trends in Perceived Racial Discrimination Among Adolescents in the United States: The Adolescent Brain Cognitive Development Study. The Journal of adolescent health : official publication of the Society for Adolescent Medicine Fields CT, Black C, Calhoun AJ, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

The Journal of adolescent health : official publication of the Society for Adolescent Medicine

Published

2025/05/17

Authors

Fields CT, Black C, Calhoun AJ, Rosenblatt M, Rodriguez R, Aina J, Thind JK, Grayson J, Khalifa F, Assari S, Zhou X, Nagata J, Gee DG

Keywords

Adolescent health, Health disparities, Intergroup relations, Interpersonal racism, Public health, Racial discrimination, Racism, Racism-related stress, Social determinants of health

DOI

10.1016/j.jadohealth.2025.03.014
Toggle Associations of interpersonal and socioeconomic early life adversity dimensions with adolescents' corticolimbic circuits, cognition, and mental health. Translational psychiatry Yang Y, Kong T, Liu R, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Translational psychiatry

Published

2025/05/16

Authors

Yang Y, Kong T, Liu R, Luo L

Keywords

DOI

10.1038/s41398-025-03384-6
Toggle The systemic immune-inflammation index (SII) as a biomarker for depression in a community sample of adolescents. Comprehensive psychoneuroendocrinology Schumacher A, Tu E, Albaum C, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Comprehensive psychoneuroendocrinology

Published

2025/05/16

Authors

Schumacher A, Tu E, Albaum C, Korczak DJ

Keywords

Adolescents, Community sample, Depressive symptoms, Systemic immune-inflammation index, White blood cells, children

DOI

10.1016/j.cpnec.2025.100302
Toggle Mental Health, Minority Stressors and Resilience Factors Among Early Adolescent Immigrant Youth. Journal of the American Academy of Child and Adolescent Psychiatry Michel N, Tran KT, Visoki E, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Journal of the American Academy of Child and Adolescent Psychiatry

Published

2025/05/15

Authors

Michel N, Tran KT, Visoki E, Gataviņš MM, Ly C, Barzilay R

Keywords

adolescents, immigrant, mental health, minority stress, resilience

DOI

10.1016/j.jaac.2025.05.005
Toggle Missing data approaches for longitudinal neuroimaging research: Examples from the Adolescent Brain and Cognitive Development (ABCD) Study®. Developmental cognitive neuroscience Li L, Bayat M, Hayes TB, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Developmental cognitive neuroscience

Published

2025/05/14

Authors

Li L, Bayat M, Hayes TB, Thompson WK, Neale MC, Gard AM, Dick AS

Keywords

Full information maximum likelihood, Missing data, Multiple imputation, Neuroimaging, Propensity score weighting

DOI

10.1016/j.dcn.2025.101563
Toggle Establishing measurement equivalence across sex, race/ethnicity, and intersectional identity for the Alcohol Expectancy Questionnaire-Adolescent, Brief: findings from the ABCD Study. Alcohol and alcoholism (Oxford, Oxfordshire) Sartor CE, Powell MZ, Kennelly N, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Alcohol and alcoholism (Oxford, Oxfordshire)

Published

2025/05/14

Authors

Sartor CE, Powell MZ, Kennelly N, Chung T, Latendresse SJ

Keywords

alcohol expectancies, gender, measurement bias, race/ethnicity, youth

DOI

10.1093/alcalc/agaf039
Toggle Developing brain asymmetry shapes cognitive and psychiatric outcomes in adolescence. Nature communications Wu X, Zhang K, Kuang N, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Nature communications

Published

2025/05/14

Authors

Wu X, Zhang K, Kuang N, Kong X, Cao M, Lian Z, Liu Y, Fan H, Yu G, Liu Z, Cheng W, Jia T, Sahakian BJ, Robbins TW, Feng J, Schumann G, Palaniyappan L, Zhang J

Keywords

DOI

10.1038/s41467-025-59110-9
Toggle Socioeconomic deprivation, brain morphology, and body fat among children and adolescents. Brain and cognition Yang A, Lu HJ, Chang L 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Brain and cognition

Published

2025/05/13

Authors

Yang A, Lu HJ, Chang L

Keywords

Deprivation, Fat Deposition, Life History Theory, Neural Development, Socioeconomic Status, Trade-Off

DOI

10.1016/j.bandc.2025.106315
Toggle Stimulant Medication Use and Risk of Psychotic Experiences. Pediatrics O'Hare K, Byrne JF, Ramsay H, et al. 2025
PubMed Record

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Pediatrics

Published

2025/05/12

Authors

O'Hare K, Byrne JF, Ramsay H, Romaniuk L, McGrath J, Keating D, Migone M, O'Connor K, Coss N, Cannon M, Cotter D, Healy C, Kelleher I

Keywords

DOI

10.1542/peds.2024-069142
Toggle Associations Among Green Space Exposure, Brain, and Mental Health and Cognition in the Adolescent Brain Cognitive Development (ABCD) Stud Journal of Environmental Psychology Liu J, Yang Y, Kong T, et al. 2025
Link to publication

Abstract

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and protective factors influencing substance use and its consequences, examine the impact of substance use on neurocognitive, health and psychosocial outcomes, and to understand the relationship between substance use and psychopathology. This article provides an overview of the ABCD Study Substance Use Workgroup, provides the goals for the workgroup, rationale for the substance use battery, and includes details on the substance use module methods and measurement tools used during baseline, 6-month and 1-year follow-up assessment time-points. Prospective, longitudinal assessment of these substance use domains over a period of ten years in a nationwide sample of youth presents an unprecedented opportunity to further understand the timing and interactive relationships between substance use and neurocognitive, health, and psychopathology outcomes in youth living in the United States.

Journal

Journal of Environmental Psychology

Published

2025/05/12

Authors

Liu J, Yang Y, Kong T, Liu R, & Luo L

Keywords

DOI

https://doi.org/10.1016/j.jenvp.2025.102625